标靶治疗的类型 – 安健肿瘤治疗中心标靶治疗的类型

What are the different types of targeted therapies?

Advances in science and technology have led to the development of several different types of targeted therapies. Each of these new treatments targets cancer through different mechanisms:

Anti-angiogenic drugs starve the cancer cells of blood that they need to survive and grow.

Monoclonal antibodies can locate cancer cells in the body by recognizing proteins that are more abundant in cancer cells than normal cells, called receptors. The monoclonal antibody may then cause its anti-cancer effect by blocking the receptor from binding with substances in the blood. Treatments that block receptors may also be called “receptor antagonists” .

Radioactive monoclonal antibodies are comprised of a radioactive substance attached to a monoclonal antibody, the latter of which acts as a homing device, and the radioactive substance kills the targeted cell.

Tyrosine kinase inhibitors interact with the enzyme (protein) tyrosine, which is active in a complex signaling system that is used by some cancers as a survival mechanism to allow them to grow out of control. The drug Gleevec® (imitinib mesylate) is an example of this type of targeted therapy that inhibits a mutated form of tyrosine kinase and stops the abundant growth of cancerous white blood cells in chronic myeloid leukemia.

Vaccines are made from a patient’s own cancer cells and stimulates the body to recognize and attack cancer cells.

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