Latest Cancer Drugs - OnCare Cancer Center Latest Cancer Drugs Intruduction

New Approved Drugs for Hematologic Malignancies and Solid Tumors:

The following are a listing of new agents approved by the U.S. FDA since 2010 and their indications.  For some drugs, their indication may have expanded beyond their original registered indications over the years.

For further enquiry, please e-mail drug@oncare.com.hk or call (852) 3588-2400

(Last updated: 6th January, 2016)

Cancer Name

FDA Approved Year

Drugs Name

Lung Cancer

EGFR T790M mutation positive

2015

Osimertinib (Tagrisso)

Lung Cancer

2015

Penbrolizumab (Keytruda)

Squamous cell lung cancer

2015

Necitumumab (Portrazza)

Lung Cancer + ALK

2015

Alectinib (Alecensa)

Squamous cell lung cancer

2015

Opdivo (Nivolumab)

ALK + Non small cell Lung cancer

2014

Zykadia (ceritinib)

EGFR mutation + lung cancer

2013

Gilotrif (afatinib)

Lung Cancer

2012

Abraxane (paclitaxel protein-bound)

ALK + Non small cell Lung cancer

2011

Xalkori (crizotinib)

Colorectal Cancer

Colorectal Cancer

2015

1) Ramucirumab (Cyramza)
2) Trifluridine/Tipracil (Lonsurf)

Colorectal Cancer

2012

1) Zaltrap (ziv-aflibercept)
2) Stivarga (regorafenib)

Breast Cancer

ER +, HER 2 – Breast Cancer

2015

Ibrance (palbociclib)

HER 2+ Breast Cancer

2013

Kadcyla (ado-trastuzumab emtansine)

HER 2+ Breast Cancer

2012

Perjeta (petuzumab)

Hormone receptor + Breast Cancer

2012

Afinitor (everolimus)

Breast Cancer

2010

Halaven (eribulin mesylate)

Prostate Cancer

Castration resistant Prostate Cancer

2012

Xtandi (enzalutamide)

Prostate Cancer

2011

Zytiga (abiraterone acetate)

Hormone refractory Prostate Cancer

2010

Provenge (sipuleucel-T)

Prostate Cancer

2010

Jevtana (cabazitaxel)

Malignant Melanoma

BRAF mutation positive

2015

Cobimetinib (Cotellic)

Melanoma

2014

1) Keytruda (pembrolizumab)
2) Opdivo (nivolumab)

Stomach Cancer

2014

Cyramza (ramucirumab)

BRAF + Melanoma

2013

1) Tafinlar (dabrafenib)
2) Mekinist (trametinib)

BRAF + Melanoma

2011

Zelboraf (vemurafenib)

Melanoma

2011

Yervoy (ipilimumab)

Malignant Lymphoma

Hodgkin’s lymphoma 2016 May Opdivo (Nivolumab) (NEW)

Lymphoma Waldenstrom’s Macroglobulinemia

2015

Ibrutinib (Imbruvica)

Follicular B cell Lymphoma 
Small Lymphocytic Lymphoma

2014

Zydelig (idelalisib)

Peripheral T cell Lymphoma

2014

Beleodaq (belinostat)

Mantle Cell Lymphoma

2013

1) Revlimid (lenalidomide)
2) Imbruvica (ibrutinib)

Hodgkin’s lymphoma 
Anaplastic large cell lymphoma

2011

Adcetris (brentuximab vendotin)

Kidney Cancer

Kidney Cancer 2016 May
2016 Apr
Levima (Lenvatinib) (NEW)
Cabometyx (Cabozantinib) (NEW)

Kidney Renal Cell cancer

2015

Nivolumab (Opdivo)

Kidney Cancer

2012

Inlyta (Axitinib)

Bladder Cancer

Bladder Cancer

2016 May

Tecentriq (Otezolizumab) (NEW)

Skin Cancer

Basal cell Carcinoma

2012

Erivedge (vismodegib)

Pancreas Cancer

Pancreas Cancer

2015

Irinotecan Liposome Inj. (Onivyde)

Acute Leukemia

Acute Lymphocytic Leukemia

2014

Blincyto (blinatumomab)

Acute Lymphocytic Leukemia

2012

Marqibo (vinCRIStine sulfate LIPOSOME injection)

Chronic Leukemia

Chronic Lymphocytic Leukemia 2016 Apr Venclexta (Venetoclax) (NEW)

Chronic Lymphocytic Leukemia, Follicular B cell lymphoma, small lymphocytic lymphoma

2014

Zydelig (idelalisib)

Chronic lymphocytic Leukemia

2014

Imbruvica (ibrutinib)

Chronic lymphocytic Leukemia 

2013

Gazyva (oblintuzumab)

Chronic Myeloid Leukemia

2012

Bosulif  (bosutinib)

Chronic Myeloid Leukemia

2012

Iclusig (ponatinib)

Chronic Myeloid Leukemia

2012

Synribo (omacetaxine mepesuccinate)

Multiple Myeloma

Multiple Myeloma

2015

1) Elotuzumab (Empliciti)
2) Ixazomib (Ninlaro)
3) Daratumumab (Darzalex)
4) Farydak (Panobinostat) (NEW)

Multiple Myeloma

2013

1) Pomalyst (pomalidomide)
2) Revlimid (lenalidomide)

Multiple Myeloma

2012

Kyprolis (carfizomib)

Ovary Cancer

BRCA mutated Ovary Cancer

2014

Lynparza (olaparib)

Thyroid Cancer

Thyroid Cancer

2015

Lenvatinib (Lenvima)

Medullary thyroid cancer

2012

Cometriq (cabozantinib)

Thyroid Cancer

2011

Vandetanib (vandetanib)

Sarcoma

Soft Tissue Sarcoma

2015

Trabectedin (Yondelis)

Soft Tissue Sarcoma

2012

Votrient (pazopanib)

Neuroendocrine Tumor

Pancreatic Neuroendocrine Tumor

2011

Afinitor (everolimus)

Neuroblastoma

Neuroblastoma

2015 Mar

Unituxin (Dinutuximab) (NEW)

Basal Cell Carcinoma

Basal Cell Carcinoma

2015 Jul

Odomzo (Sonidegib) (NEW)

For further enquiry, please e-mail drug@oncare.com.hk or call (852) 3588-2400

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